CYANA

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Combined assignment and dynamics algorithm for NMR applications

CYANA ((c) by Peter Gu"ntert) is a program for automated structure calculation of biological macromolecules on the basis of conformational constraints from NMR. The combination of automated NOESY cross peak assignment, structure calculation with a fast torsion angle dynamics algorithm, and the ease-of-use of CYANA provide for unprecedented efficiency in NMR protein structure determination.

CYANA2.1:

Availability:

References:

CYANA2.1:

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Availability:

  • CYANA is available exclusively from LAS. The current version is CYANA 2.0.
  • System requirements
  • Prices
  • Get CYANA 2.1!
  • The current version is CYANA 2.0. CYANA 2.1 will be released in the first week of July 2005.
  • The upgrade from earlier Cyana (not Dyana) versions is free-of-charge.

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References:

  • Gu"ntert, P., Mumenthaler, C. & Wu"thrich, K. (1997). Torsion angle dynamics for NMR structure calculation with the new program DYANA. J. Mol. Biol. 273, 283-298.
  • Any reports or publications of results obtained with CYANA must cite this paper.
  • Herrmann, T., Gu"ntert, P. & Wu"thrich, K. (2002). Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA. J. Mol. Biol. 319, 209-227.
  • Any reports or publications of results obtained with the CANDID module of CYANA must acknowledge the use of CANDID by citing this paper.
  • Gu"ntert, P. (2003). Automated NMR protein structure calculation. Prog. NMR Spectrosc. 43, 105-125.
  • Gu"ntert, P. (2004). Automated NMR protein structure calculation with CYANA. Meth. Mol. Biol. 278, 353-378.
  • Jee, J. G. & Gu"ntert, P. (2003). Influence of the completeness of chemical shift assignments on NMR structures obtained with automated NOE assignment. J. Struct. Funct. Genom. 4, 179-189.

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